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Perhaps even more concerning, sales for Amgen's top-selling drug, Enbrel, were flat in the third quarter of 2016 compared with the prior-year period. Enbrel faces stiff competition in the autoimmune disease market.In addition, the U.S. Food and Drug Administration approved Novartis' biosimilar to Enbrel in August 2016. So what's the good news? I'd put the positives for Amgen into two categories -- financial and future. On the financial front, you won't find too many biotechs better-positioned than Amgen. The company spins off operating cash flow of nearly $7.3 billion. Amgen reported a cash stockpile (including cash, cash equivalents, and marketable securities) of just under $38 billion at the end of September. Amgen has been using its excellent financial position to buy back shares, spending $2 billion on stock buybacks in the first nine months of 2016. The company is also one of only a handful of biotechs to pay a dividend.

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